My next guest, Carolina Reis Oliveira, is the co-founder & CEO of Oneskin, a biotech company developing solutions to target anti-aging at the molecular level. Carolina holds a Ph.D. in stem cell biology.  OneSkin is leading the development of the first anti-senescence topical product designed to promote skin health and strength. Carolina has been actively engaged in the longevity ecosystem in the Bay Area.

We talked about:

  • How she journeyed from a small town of 7000 people in Brazil to Silicon Valley. (and why Peter Diamandis is betting big on her stemcells)
  • How the academic salary cap pushed this Brazilian rebel to come to America and form her VC-backed startup.
  • How she unifies her scientific training and spiritual faith to (confidently) navigate startup uncertainties
  • The secret advantage Carolina didn’t know she had that would save most entrepreneurs years of pain.
  • How she and her 3 cofounders engineered healthy founder dynamics and workplace culture for the last 5 years
  • And finally their unique inside-out approach to anti-aging that’ll help us live to 120

Links

Full Episode

 

Wisdom Quotes

Aging is the main risk factor for all of the diseases that most of the diseases that we are trying to treat. Click To Tweet You can do whatever you want. You have the potential if you dedicate your life & if you put your heart and soul into it. Click To Tweet Go out and talk to people. The opportunities will come to you as you put yourself out there. You'll be surprised how much people are willing to help. Click To Tweet Ignorance is part of this evolution. And to me, my spirituality helps me to fill in that gap. Click To Tweet We learn much more from our mistakes & from the times that we are suffering than from our happy moments Click To Tweet If you listen to your body, you can get insights and messages. Pay attention to them because they bring you clues or ideas that you should pursue. Click To Tweet When you clear your mind, you get to a clarity state and you get different levels of understanding. Click To Tweet Running a startup is a marathon and not a sprint. If you burn out yourself, you're not going to get your company anywhere. Click To Tweet The CEO is the North star for the company. Making the vision we are creating so clear and meaningful to all of them that it's natural for them to work and give their best for this company. Click To Tweet

Episode Transcript by AI

Carolina Reis Oliviera Transcript by AI

Create Better ways of Living And Aging

Welcome to Nobel warrior. My name is CK Lynn noble warriors, where interview consciousness center entrepreneurs about their journey from warrior to commander to King will deconstruct the mindset, mental models, actionable tactics. So then you can take them in and build your own business with more impact and fulfillment.

[00:00:19] My next guest is Carolina Reese. She's the co-founder and CEO of one skin. The first STEM cell anti-aging cream company. One skin is the company. Peter Diamandis is betting on to help make living to 120 years old with vibrancy possible. We talked about how she journey from a small town of 7,000 people in Brazil, all the way to Silicon Valley.

[00:00:42]How the academic salary cap pushed this Brazilian entrepreneur to come to America to form her VC back startup and how she unifies her scientific training and spiritual faith to confidently navigate startup uncertainties. The secret advantage Carlina didn't know she had, that was saved most entrepreneurs, years of pain.

[00:01:05] And how she and her three co-founders engineer, a healthy founder dynamics and workplace culture for the last five years. And finally that unique insight, our approach to anti-aging that will help us live to 120. So please enjoy my conversation with Kelly net Reese, the CEO of one skin. 

[00:01:27] Create Better ways of Living And Aging: [00:01:27] I want to first congratulate you for being feature in nature biotech a few days ago. How does it feel to be recognized by one of the top science publications? Yeah. As a scientist, we always have some. And that's definitely the future and nature is, a great recognition of the work that we're doing.

[00:01:59] So we usually read Noe, inspire our research, reading nature. Nature publications. So the fact that we were featured there means that we are not only doing something that's right, but other people are appreciating our science. And we though believe that the science is in the frontier of this longevity technologies that will completely change the way that we age, the way that we perceive aging and the, yeah.

[00:02:34] It's, It feels yeah, we feel like very proud of our work to be featured in such a, great journo. Awesome. So when I was doing my research around you and your company, I came across a few interesting things. Well, one of them is the documentary that you made around one skin. And what actually is impressive to me about what you are trying to do is not just, Hey, let's help.

[00:03:05] People to be more beautiful. That's an important part. Everyone loves to look good. So, that's great. But an underlying theme that I hear is you said, quote, living a healthful, joyful life as long as possible. And I really, really love that. Can you say a little bit more about why that is? Am I accurate to receive that?

[00:03:27] Is that an intentional thing, purpose that your company is trying to do? Totally. As we decided to focus on Tivity our, and this aligns with my personal and professional goal, I always want to. Work with science or develop science in order to improv to improve people's quality of life. So I always want to work with health for humans, how we can eventually cure disease and, or find better ways that people.

[00:04:08] Can have more better health during their lives. And when decided to do, to study aging and longevity we realized that this could impact so much our health as a whole. And Eskin is one of the first applications for this technology. And by treating. Can aging. We learned so much of the importance of the scheme for our overall health.

[00:04:39] And also we were always focused on improving the health of the skin in the molecular level. So extending the time that our skin is functional and extend or improving the resilience of our skin. And so they skin protect us against infections against water loss, and I guess all types of threats and the consequence of three things, all of these processing, the molecular level is that you are going to look better because they are younger skin.

[00:05:16] Usually it's a skin that looks better and it's functions better. But as I said that we are starting with skin, but we see that our technology can be expanded to other tissues and our messaging. And now our mission goes beyond the skin. We really want to provide means that people cannot live longer because this, we are readily using, but we are not living better.

[00:05:43] And what's the point that we reached like a hundred or 120 years is 30% of that time, we are spending fighting or suffering from a disease. So our goal as a scientist, and as I found out one skin is really to develop those technologies and also bring information that will help us to make better choices.

[00:06:08] So we can close the gap that we have good health. And the time of the total time that we live in this planet. 

[00:06:20] Now, before we dive into more on the technology part, cause I can go with you about the specific space, why then, and all that stuff I want to ask you about the found their product market fit.

[00:06:33] Like why you, what inspired you to. Get into well skin, the first place, is it, is there a specific reason is specific memory? Is there a specific desire? Like why skin out of all things or devotee of what out of all things. Yeah. So as I said, when I was. Still like younger on on high school. I always loved science and I want to do something related to science to affect or impact people's health.

[00:07:11] And one of the fields that I was very passionate about was the STEM cells. So I. I decided to develop a project on my PhD that was focused on STEM cell biology. And I saw so many opportunities to apply that research. So for example, my PhD was focused on producing retina cells, derive it from STEM cells so we can transplant and prevent people for getting blind.

[00:07:42] So to treat or to prevent macular degeneration. And then when I was saying that she might PhD, I want to to start my trip in Europe career. And I joined with my two colleagues and the, we had a similar background and we saw that. We could definitely use the STEM cells to treat the disease, but a faster application to bring this technology to the market was going to use the STEM cells to produce human tissues or small organs that we could then replace animal testing.

[00:08:19] So since I had the expertise in retina, my call found that have had an expertise in building Many hearts. So we could produce like cardiomyocytes that would be in the lab. Super cool. And then we could test drugs and then evaluated toxicity and efficacy and so on. So this approach of building a human thesis to replace animal testing attract more the cosmetic industry, because that was the main industry that was suffering.

[00:08:54] Fresh or from the population to really stop doing animal testing. And then I had another colleague that had the experience in growing skin in the lab. And then we decided to start, the buildings came to meet this need of the market. And to us was a very novel purpose. We also want to be more ethical as a scientist.

[00:09:19] So if we can use human tissues, why testing animals and mainly for cosmetics, so that's how we are attracted for this market and in the process of trying to eventually the company evolves and in the process of finding product market fit, we decided to focus on the anti-aging market.

[00:09:43] And in order to solve the problem of the anti-aging market that's which products work and which don't how it can validate the efficacy of those products. We needed to start to study about aging. And, then when we sit, when I start to study about aging, I realized that's what I should focus on because.

[00:10:08] I realized that aging is the main risk factor for all of the diseases that most of the diseases that we are trying to treat. So if I want to treat macular degeneration, if I want to treat cardiovascular disease, the common cause is aging. So if we can do something about aging, we can create a much bigger impact and.

[00:10:30] Even better, we can extend the time that we are free of disease and it's that instead of trying to treat the symptoms, that's what the healthcare system does today. So everything starts to the doctors start to connect and I saw, yeah, that's what I'm supposed to be doing. And I'm also a person that.

[00:10:53] I strive to enjoy every second of my life. And I can't imagine that aging will bring me limitations. I can't do this or that because I'm getting older. So I want to do something about it. And I want to allow people to be able to live that healthier and more fulfilling lives until they are the last days of their lives.

[00:11:20] So I think it doesn't make sense if we spent a significant part of our lives not productive or not healthy or not enjoying the time that we are here. And that's where I think I can contribute. Thank you for that. That was a beautiful answer. I think that, Brazilian part comes out right?

[00:11:44] That passion for life that drive to V joy for life comes out. We're really helping people, not just live longer, but having a shitty quality of life longer while maintain great quality of life so they can move more and do more and be more during this time that we have limited amount on this planet.

[00:12:05] I love that. Yeah. So thanks for sharing. Yeah. Like we, we are very in Brazilians, we are full of energy and we have this yeah. This lifestyle of enjoying life and so that's the thing. That's it's part of my DNA. But to me it makes sense, like to spread these, I think everyone should be enjoying their lives as much as possible.

[00:12:36] So for that, yeah. 

[00:12:40] So, I want to ask you even literally. A little bit deeper here, because this is your second company. And you started as a PhD at the before, you even finish. If I recall correctly finish, and then you started it and then you started another company and you came all the way from Brazil to here by yourself.

[00:13:02] So I would say it's probably something even deeper than, Hey, I just wanted to serve in market opportunity product market fit, that kind of thing. Because one, I had come to this country by myself and it was challenging. So, if you can go even a little bit deeper what is the fire within you?

[00:13:26] That's burning to say, I want to start a company. So you made the kind of difference in people's life. Yeah. So when I was in academia doing my PhDs, I was seeing the path past that I ha I had that had me. So I could pursue an academia academic career, or I could work in a a pharmaceutical company, a biotech company, or I call the build my own way.

[00:13:59] And. The academia. It was definitely not like the future that I was seeing myself. I, to me, I really appreciate the basic science and all the, everything that they do there. But to me was not enough to fulfill myself if all the research that I was developing. It's going to be transformed in papers and not people won't be benefiting from that research.

[00:14:25] So even the past research that I did, for example, my master, I worked with vaccines and it was like so much work and in the end it didn't go anywhere. So it frustrates me so much and I could spend the rest of my life like doing this. So I said, okay. And then if I go to a pharmaceutical company, Yes, that could be a way that I could apply my research.

[00:14:50] But then I saw my brother that was younger than we starting this he's an entrepreneur career. And the, and they stopped like with a, a big project. They were going to transform like lands and areas for reforesting. Growing trees and then they would. So the, piece of land and the woods that they wouldn't harvest from those trees.

[00:15:15] So I saw them going from an idea and now almost like giving up that to a point that people said, Oh, you guys started thinking too big. I think you guys should return the money that you could the race and maybe start like smaller. And eventually they could get around and overcome that.

[00:15:36] And today they have, I don't know how many what's the size of the land, but it's so beautiful how they transform the area that they are in the greatest, so many jobs. And they're really changing the ecosystem around then creating value and, seeing that. Going from an idea, almost like giving up and being able to overcome and to generate all this was like, so inspiring to me that I said, yeah I want to do something like that to know.

[00:16:13] And another way that the I didn't that's made me to pursue my own intrepreneurial career. I remember I was always listening to this intrepreneur from Brazil and he was saying that he doesn't want. To anyone to tell him how much he should be paid. And in academia and as a scientist, usually this is a profession that's not well valued in the market not like engineers.

[00:16:45] And so scientism, PhD, sometimes they are like, that they'd Farley. And I first, I agree with that instead of I'm not gonna follow those rules, so I'm gonna create my own rules and so I, everything combine and I decided to Starting my own journey and doing the things that I believe that I could do best.

[00:17:13] And yeah, here I am. So two things that I hear, one is. That Brazilian spirit. That being like a rebel right there. It's coming out strong. And also you had the brother as an inspiration, and then you said to yourself, if he could do it, I could do it. I want to do what he does. Yeah. Very accurate.

[00:17:37] I love that. So I'm a former academic myself. So everything you said, I completely. Empathize. And I understand, I don't want my life to be measured in how many papers I published. It's I actually want my life to actually make an impact on people's lives. Hence why I switched gear to entrepreneurship and, spare very fulfilling that way now.

[00:18:01] If you were speaking to the younger Carolina, who may think Oh yeah, I would just go have an idea and create something new. What would you say to her? If you can speak back to that academic, technical PhD, Carolina, what would you say to her about this journey that she was about to take on?

[00:18:27] Wow. I would say first that Carolina, you can be, and you can do whatever you want. You have the potential, if you dedicate. Your life. If you put your heart and soul, you, I never thought that I would be here today in Silicon Valley leading a biotech company, this and that. No one likes said to me that I could get here.

[00:19:04] If I dream of that, I was like, wow, maybe today I look to the younger girls and I tell them if you want to. The people that are from ICD. I come from a very small city in Brazil, 7,000 people. And

[00:19:25] yeah, so there is only one like public school. Like you don't have many options and you think that your world is it's restricted to that. And today I tell them and I say, no, you can go. Whenever you want, you can be whatever you want, you just for your mind there and all work together.

[00:19:52] So I think in the beginning, I didn't believe that I was capable to get here. In the beginning, I was always like, I need my co-founders. If they are not with me, I can do that. This is so hard. I don't know how to do it. I don't know. Even like in the beginning, even I how to speak English properly. So everything was like, I had a lot of limited limitations in my mind that was Both anything made to take, I would say to be both like to take higher risks, even though I was always like down to try everything.

[00:20:33] I think a lot of times I was a little resistant that so I, today, and I remember I was scared. I was afraid when I needed to speak up we or like talking with microphones, just I don't think this is, it's so hard to be because I didn't believe in myself. And so I will definitely say that.

[00:20:59] We are capable of a two thing, whatever we decide to and if people that want to be in that journey, we feel, and you'll find the people that will align. If you're a vision throughout your journey, this would be one piece. The other face, I would say. Is that a lot of times I avoided several hard conversations in the beginning.

[00:21:35] I think this is part of the human being, trying to be or not everyone, but I think I'm. Very much, like not confrontational. And I tried to be nice with everyone, but I confused things in a way that's to be nice. It's not two o'clock things that need to be discussed and need to be thought.

[00:22:00] And I had so many yeah. Challenges and diff difficult times with the team and everything. And, a lot of it came because we missed two or we have five of those hard conversations in the beginning, even know we were not super honest and clear in the beginning to say this is what I want for my life.

[00:22:27] Why do you want to like how it can, is there a way that we can align our dreams and we can still work together? Or if not, that's fine. But I think we can hope that people will have the same. Behavior or they will take maybe the same risks as you and, with time, you'll learn how to understand that and understand that if you find that that, middle ground that come round where people can align where their head there or where they live, yeah. They feel that they are in their place. We, they, the work that they can bring to the company, I think that's where you can get to the most of it because you can't force people do what you want because you think that's the right for the company, offer them. And it's yeah, it is. It's something that I learned throughout this journey.

[00:23:34] So before we get to the specifics about how you have. Three co-founders. So the four of you together, it's very similar to getting a long-term marriage with three other people, right. So that in itself. So I'll go back to ask you the tactical ways for you to come on, come together and work nicely. But I want to go back to the younger current.

[00:23:37] Yeah. Your advice for her is to take more risks, be more bold and yes, she's smart. She may have an advanced degree already, so she intellectually knows that, but how could you, how could she right. Go out and take more risks. You had mentioned find people who align with the vision. So that's great.

[00:24:00] So having a great peer group, right? So that's helpful. Any other tactical ways to empower the younger versions of ourselves to take bigger risks?

[00:24:17] I think a lot of it is go out and talk to people and The opportunities they'll come to you as you put yourself out there. So a lot. And I, learned this even here in the U S for sure. A lot of what do we. We have today it's basically a result of the connections and the work that you develop and the partnerships that you create and your mentors and people that will connect to with investors or Other people that can help you.

[00:25:01] So I think it's okay. So maybe that's the summary of this. Ask more for help. And don't be afraid of saying I don't know anything about how to be an entrepreneur. I don't know how to start. For example, very recent to the, beginning. I didn't know anything about how to get into intrepreneur. But very recently we needed to start to build the brand and I didn't know anything about how to build a brand.

[00:25:28] And I think even recently I could have gone to people and say, I don't know anything about how to build a brand. Can you help me, or do you know anyone that can help me? I have this, I need to get there. How I cross this. And the same when you are starting coming from the academia, we have, at least I didn't have no idea how to start a company.

[00:25:59] And I learned as we started to develop our own project, but. If you have people around you mentors and advisors, and if are part of a group that's talking about the same thing every day, you'll learn so much faster and asking for help, I think is the first act of showing that are not only humble, but you were Eager to learn.

[00:26:36] And this can definitely accelerate to your progress. Thank you for that. So you actually had mentioned talk to people and then opportunities come to you. Now we're getting into more of a spiritual realm here. So I'm curious to know, as you talk to people, what can you give us a concrete example of, Hey.

[00:27:00] One opportunity or in connections or one things that you never expected came to you? Yes. So when I was here in the us. I was at the Dubai as these parts of this acceleration program. And then I went to one of the things that, there was exposition it's about biotech. And so there was a Brazilian A Brazilian kind of hub. And then I connect to this guy Fernando and he said, wow. And I explained what we were doing. And he said, wow, are you serious? Do you grow humans teams? Who are you? And he was like, okay, I need to give some aphasia to this girl. And, then he connects to other people. And then eventually I, was part of another program and in the end I was presenting at tech crunch, disrupt we've a lot of other startups and in the end that they select the best presentation and I won and I was like, wow, I do, even though this was like a competition, but.

[00:28:19] After I won this presentation, a lot of doors open to me. I was super new here. I didn't know many people. So Fernando was one person that I shared my story without expecting anything. And he, was like ready to help and commit to this competition that I won. And this changed our our theft here because a lot of people connect to us and they were interested in.

[00:28:55] So I got our lawyer and I got to present it to other people that I connect to our future investors and the. We started to build our name, to build our credibility here. So this was one example. And then I had another guy that I connect in this day, in this event that he organized Presentations to people, to investors.

[00:29:22] And in one of this presentation, I met my first investor. So these two people there are so many, there is I was also presenting in Brazil was, and I. No, this guy that connect me with the people from India. So coming here to the us also like completely changed our lives, my, our lives. And if I was not out there presenting the company in every opportunity that I had and trying to talk to people and trying to share and sharing.

[00:29:57] What we were doing, I would not connect to this guy that would connect me to in the bio. I will then come to the U S I I wouldn't be here today. So the Mar that to your, you put yourself out there, I think the better, the chances of finding people that will help you and you'll get surprised how much people are willing to help.

[00:30:20] It's. It's so nice. It's so beautiful. So one thing, a quick recap. So you're clear about what you wanted to do, right? To explore the properties or the possibilities of anti-aging possibly through STEM cell research that you've done. And then you're clear about that and you started to show up more. You take action, you have conversations with people and you are humble.

[00:30:44] You ask people for help, and then you find a lot of great. Mentors or connections who's willing to help you. And then you allow for certain tipity accidents, cosmic accidents to happen, then you just follow your flow that way. Is that an accurate recap of what you did? Yes. All right. Beautiful.

[00:31:03] So here's the question. Okay. So as a PhD person we tend to be very analytical, right? And, you need to have evidence or data before you take the reaction, right? Quote, unquote, strategic. That's a nicer way to talk about it. A nice, not so nice way to talk about it would be. We tend to over analyze things a lot.

[00:31:31] However, where are you going to share? Is. Very much not that right. It's very much surrender, mean flow, trust and faith. So share with us a little bit about how you navigate. The two worlds of having data to take action. And at the same time, allow yourself to be in flow and being surrender and trust and have faith.

[00:31:54] Tell us about that. Yeah, definitely. So when we started we, needed to define or to design some kind of structure, right? So how we're going to start. So first thing, we start to looking for accelerators that we could be part of that we could get mentorships. So initially we, worked back up to accelerators back in Brazil and in one of those presentations, I got the.

[00:32:24] The opportunity to connect to indie bio and that's how eventually we were accepted and he came to the us. So you need to have both like your plan I'm going to do, if I want to get there. W what is the the route that I think that can really help me to get there faster. So you'll, need the Cho.

[00:32:50] Check ride some boxes. And then as you learn on your way, you are going to see, okay, I have a little bit of a financial resource. I have this infrastructure I have How is it that chronology? How did the product, and then you are trying to understand what are the pieces that you need to get in place, so you can start to, advance your project.

[00:33:22] So it is a combination and it is. Often this more structured process with this Sarah, and  that you will find along the way, putting yourself out there and talking to people And I think I am I am a scientist and I'm, I have this mind, that's very analytical, but I'm also a very spiritual person.

[00:33:53] So I know a little bit how to balance and you needed that. At least I need that to have this. Faith, because even being analytical, a lot of times things, will go wrong and we'll go, as you expect, and you don't you hope it wasn't a different way. And you need to have that kind of, at least I needed that faith that will help you to go through and to believe that.

[00:34:26] This has got, does this a face you're going to overcome these you're going to work to get better to learn and to get things right. Again. But a lot of times things will, happen in a way that even doing all the planning, a lot of times you can't control everything and learning how to deal with the situation that you can't control, even when you are doing your best.

[00:34:54] And you are trying to, find the right answer or to a lot of times it takes time and. If I needed that internal certainty or that termination that I should keep going, that eventually things will fall in its place and everything will start to make sense. So it's it is a combination.

[00:35:24] Yeah. If you could say a little bit more about that, so I'll share my experience real quickly. When I first started as a scientist, I felt the world is pure materialist. So if I don't have data, then it doesn't exist.

[00:35:38] So anything even like emotions, what's that I don't have data to measure my emotions. So therefore let me be as robotic and stoic as possible because I needed data. And then the more mature I get that I'm more like, I've come to appreciate. Oh, the emotions actually are very, important. My, friend said it best.

[00:35:59] He said, imagine who you are as a spiritual being, living human life, your mind, your body, your heart, and your spirit are for boosters for this rocket. You could just use your mind, but since you have all four rockets, why don't you use or four it's Oh yeah, of course. That makes a lot of sense. Duh, so when I came to appreciate it more and more about. This whole idea of things beyond data. Cause he my, spirituality essentially, or faith is you believing things that you don't necessarily have data for, right? That's beyond the boundary of your understanding. And therefore once I have that component and then it calms me down a lot, because then I can trust this entire human journey is already there.

[00:36:48]Challenges, conflicts, failures that I face is all part of the journey for me to learn as a human being. So that actually allows me to be able to do the ying and the yang harmony very well. So in my mind is actually not a paradox. It's not either you're a spiritual person or you're a science person.

[00:37:14] It's. Actually both. So I'm curious to know your thoughts about someone who's thinking how can you be both spiritual and, a hardcore scientist? How does that work? How would you respond or add to what I just said? So what I think is that as a as a human being in, this. On this plane we are here to evolve and we are seeing how humanity is evolving, right?

[00:37:46] How our brains evolving, how technology is evolving and would be very I don't think we could assume that we could have answers for everything yet. I think. Ignorance is part of this evolution until you get to understand a lot of things that you can't explain to them. And to me safe, and my spirituality helps me to fill in that gap.

[00:38:20] I th I'm sure that everything that there is an explanation for everything, but. I don't think a lot of times we are in that level to be wise, and also to be able to understand why this is happening and the being humbled. Accept that and trust that we want their stand at the right time.

[00:38:47] And that we, this doesn't change the fact that we are going to still continue to do our best. And we are gonna certain pursued this evolution, but we don't need to have all these answers to So to live here or to to believe that things can happen then. And that's how I combine.

[00:39:11] And this really helps me because. And, I believe in this superior intelligence, that's running everything. And, that a lot of times we see that everything in the ans makes sense and it's for our best right. Everything that happened to our life. If you look back, you see which time you understand why that's happened.

[00:39:37] So it seems that there is something much bigger than us, like that knows what's best. And, that's what I do. I trust that superior intelligence and one day we will understand, but I don't need to have all the answers right now. 

[00:39:57] Yeah. I think one of the key ans key questions that a lot of people ask in these types of conversations is, Hey, if you can go back.

[00:40:07] Past, you want to change anything. And my younger version of myself would say, yeah, I want to change this and that to alleviate pain and suffering that I experienced, I would be my younger self to answer, but today I will answer, I wouldn't change anything. And I, actually saw everything as a, blessing because who I am today, everything that I earn, everything that I.

[00:40:33] Oh, the wisdom that I have the experience of this human experience, because I had all those things. So I wouldn't change anything. I have nothing but love and, gratitude for any of those things as, unpleasant as they were before. So I'm curious to know your thoughts. Would you change anything in the past, if you could advise the younger version of Kimberlina, what would you say to her?

[00:41:00]If I had, if I would change something, I think I would still need another's similar, challenging situation. So as you said Oh, the thing, and the hard times. They made me to grow and they made me to be a better person. So I'm so much more appreciative for a lot of things. And I have a better understand the NMR empathic in fact that Eric because of the things that were very hard to meet the past.

[00:41:37]So if I was not challenging by those situation, I think I wouldn't be the person that I am today. And I believe that I'm a better person today than yesterday, than 10 years before. So I don't think yeah, everything that happened in the end was the right thing to happen. And I like this Saying that you are on the right time doing the right thing and you need to go through this if I experienced this situations.

[00:42:11] So yeah, 

[00:42:13] let's actually use our scientists hat on for a moment 99% of the time, or 90% of the time of the experiments is what failure. So everything that we do needs to be. Quote, unquote, success is ludicrous. I design. If we're pushing ourselves to grow, if we're pushing us out to have a breakthrough by definition, you go through a barrier.

[00:42:39] And so there that barrier is that internal resistance or external resistance. Curious to know your thoughts anything you wanted to add or do you agree? Disagree? When I think of being a scientist is a great training to be an interpreter or even to be a lot better person because you'll get used to, if you don't get to use, or if you don't learn how to do it the failures You don't do science and a lot of times you repeat the same experiment, same conditions, and you have completely different results.

[00:43:17] And that thing like kills you. But if you don't have the patience and even like the curiosity of trying to understand and try to study more and see where the problem can be coming from And if you don't have that persistency, you are not going to get to a, any breakthrough. I think everything that we have today, they are a result of millions of failures.

[00:43:48] And these are the most, in fact impactful things in our lives. So we learned much more from our mistakes from the times that we we are suffering then from our happy moments are happy or just in China. And that's great, but the it's really pushed us to be a better person are the hard times.

[00:44:16] So, so on this podcast, a lot of the times we do talk about our dark moments. Some of my especially entrepreneurs, rarely, I hear entre because as a CEO, one has to be project. This bright, shiny smile. Everything's great.

[00:44:35] So rarely they have a chance to talk about dark moments because they couldn't be human. They have to be quote unquote CEO. So on this, we do get into the dark moments and some of the entrepreneurs that I've spoken to on this podcast, they share, Hey, When I'm able to raise funding, women companies going great.

[00:44:57] My self esteem is super high, right? And then when I couldn't raise funding at all my facing darkness and when I'm have to hire a fire people or when I have doubts about. Whatever the direction of the company or co-founder conflicts and things like that. It was really, depressing. Cause I had no one to talk to and some of them are even contemplating suicide.

[00:45:22]During your dark times, Tran from your journey from PhD scientist to founder, to now CEO could you share with us perhaps one dark moments and how were you able to keep that faith, keep that resolve to continue to move forward in spite of however you feel and insight?

[00:45:50] Yes. So I had to marinate. Dark moments mainly in the beginning when I moved to here. So I came by myself without knowing a single person in San Francisco and We didn't have a technology ready to be deployed, or so we were still finding our product market faith, where we would really build something.

[00:46:20] Where would we go to really create value? And in the beginning was hard to find them. We were getting a lot of nos and we were not getting traction and the, and at the end, the bio, every Friday we have a, what are they called the killer of the week? And you need to show, or to present something that you achieved that week, or you are screwed like you're screw.

[00:46:48] They brought them kind of everyone. Every Friday was like a terror for me because I needed to have something. And a lot of times I was like in the lab at 11:00 PM on Thursday night, trying to get that result. Then there was the experiment, the Oregon's a dam and what I'm going to present tomorrow.

[00:47:10] So it was like frightening every Friday. Oh my God. Say something. And in the beginning it was hard. Like we were not getting good results, we're not getting traction and so on. So every day I made the like tomb get all the pieces that were like falling apart and put together and let's keep going.

[00:47:33] Let's keep trying. And, we were eventually we started to get some. Good feedback. And I remember this was like a presentation  two weeks before the days. So I decided to change a little bit. They story, they started telling of my pitch and in the end, the presentation went well, but they started did them lay you out.

[00:48:02] Yeah. I remember that too. One of the managing partners said, Carol, this is a disaster. You are not going to present if that's what you're going to bring to them, or they are not going to present. And I was like destroyed. And I remember that the. At that day people that were in the audience, they could give like fake checks to the companies if they were going to invest and we were the only component that they didn't get to any money.

[00:48:38] So we were there one like in the last, in the room and that day I was devastated. I was the only day that I really cried at that also wow this, day, I still remember. And then I decided, okay, of course I'm gonna I'll be able to overcome these, how I will do another presentation and in 15 days I have, I had done that and I was presenting they stage.

[00:49:09] And in the end of his said, Kara, I'm proud of you. You did very well. And today he's one of my my main mentors. And he has two young daughters and he says that today I am a role model or his daughters. But that day was a very dark day to me because it was clear to everyone that I was like really failing.

[00:49:42] But in the end, like inside me, I knew that I was going to. Be able to turn that around. I was going to be able to basically start over and the, and overcome that, then I would get to the other side. So pause. 

[00:50:05]I think a lot of people could relate to that whether they were in academia, or startups, or even as an employee right now, Yeah, that feeling like that sinking feeling of Oh my God, what am I going to say?

[00:50:22] Any authors, speakers, scientists, I don't care who you are, have all experienced that. So w what practices did you have to keep going? So you cry. So that's one practice, right? What other practices did you have allow you to go from the last, in the rank? To keep going and then be one of the first I would say

[00:50:50]I of course I had that day that was very hard, but the next day I was like you'll dry your tears and you put yourself like Back together again, and you'll, go to, solve the problem to face the problem. I can't hide this. If there is something that needs to be better, let me work on this and let, me ask for help and let me do my best.

[00:51:21] So I was. Keep something that never passed to my mind was like the option of giving up. So I knew that there will be this very down moments. The. The next day. And again, my faith really helped me to get through those moments because I knew that I was doing what I was supposed to do.

[00:51:57] I was. This is, I could feel that I couldn't do be doing anything else when I thought about, okay, if this doesn't work What it's gonna what I'm going to do with my life. And I was trying to picture myself maybe going back to Brazil or working in kind of an innovation hub or something like that, talking about pharma of Silicon Valley experience.

[00:52:29] And I didn't see myself doing any of this and and then you'll bring yourself again to the present then think, no, This is going to work no matter what. So let, me keep it doing my best. And I want to underline something. So you, cry and you probably rested, right? And then you settle and you start to project for of, if this doesn't work out, what could I do?

[00:53:00] Innovation hub and. You couldn't imagine that's what you'd be doing. I would imagine probably some visceral reactions. You're like, ah, I don't want to do it. Okay. No that's, not the path. Let me go back to solve this problem. Is that an accurate reflection?

[00:53:19] Yeah. And I can picture myself like having those thoughts where I was at and I can clearly. Re see myself okay, this, I can see myself there. So let me focus here and also let me do my work here and keep going. Sometimes, you just need to have Strength enough to go to those hard times it's that time that you feel almost so weak that you can do and you learn that you can like you can go a little further.

[00:54:01] You think that your limits are here, they are further and you keep pushing them. Are there practices that you have Prayer meditation, yoga, walking in nature, going to sleep cold bath, sauna, boxing. Any of those things that, yeah, I would say meditation for sure. And. And I always go I, always go to a spiritual church also like every Sunday now with COVID it's like a virtual church, but these Sunday routine help me to recharge my energy and even to get confirmation From the spiritual world that I'm on the right path.

[00:55:00] And I should I should keep doing what I'm doing and eventually things will out. So if I didn't have that confirmation that comes from these, the spiritual source. I dunno if I would keep going, because sometimes you doubt yourself, right? Am I doing the right thing? I'm on the right place.

[00:55:26] Should I do something else and you feel have, and a lot of times you can get this from your your gut feeling. If you listen to your body and you feel, try to analyze your reactions You can understand that, but if you can get this message from and, we learned these in this church that I go all these insights that we have and this we need to pay attention they come because they are help for you.

[00:56:01] So if we don't pay attention to what are we yeah. Those kinds of spontaneous ideas that come to our mind, don't get NAR them like pay attention to them. They can, come to bring you like a clue or and idea of something that you should pursue. That's gonna really, yeah.

[00:56:28] Open away for you. I like that. Yeah. Keep our inspiration going follow trust and follow our inspiration. Our curiosity. Yeah. Yeah, exactly. They attention more on the thoughts that comes to your mind, because for example, when you are meditating and you first, you clear your minds off your thoughts, that are populating your mind, that work and problems and family. So when you clear your mind, you get to a clarity state and it start like getting different levels of understanding. So I think if we make more time to get this help this kind of connection is a static connection and you, need the, to be peace. We need to be. And I stayed to death. Your vibration is high because you can imagine that the higher, your preparation, the better are going to connect with higher levels of energy. 

[00:57:40] What are some of the practices that you have to keep your vibration high physically, mentally, emotionally, spiritually, other than going to church?

[00:57:49]Cultivating positive thoughts nature, cultivating positive thoughts, like what like, a journal that you would have something that you read. Can you bring it down to someone who's listening to you who don't know you yet? What specific rituals do you do to cultivate that positive thought?

[00:58:15] I think as an interpreter, usually we are over optimistic. So we already have this optimistic vision about life in general. So if everything is going wrong, you still can find silver linings and you can still find ways to be grateful for whatever is happening to your life.

[00:58:41] And you feel can ride those down. You can even make it more clear to the universe, then it becomes even more like tangible, more real. Practicing, read Reddit, I think. Yeah. Even in the hardest situation. For example, when I lost my dad was like probably the hardest thing that happened to my life.

[00:59:07] Finding gratitude was a way to that help it made to to go through that dark time because otherwise it's, so it's like everything, like you, you lose the, the, sense of the life, the meaning of life, the know it feel. And when you start to cultivate in your practicing that the gratitude like, Oh, I had the, him in my life for 33 years.

[00:59:40] He's this amazing person that, Lasted this beautiful legacy. And I learned so much. And if I can be one third of if I can be a little bit like I'll be I'll have accomplished my mission in this earth. And I was so lucky to have him as as my father like I, he, I grew up learning Having him by my side.

[01:00:13] So when it's hot, like finding ready to it's in a moment that is so hard it helps to grow, to go through. Thank you for sharing that. Your dad did an amazing job.

[01:00:34] Yeah.

[01:00:38] Yeah. He was an amazing person for sure. Any other practices that you have, how's a way to cultivate high vibration for you?

[01:00:52] Yeah, I think also again, being nature Matt, if you can combine meditation nature you, can both have the the energy and the, base of mind that really helps you to to. Release any kind of stress. So if I can, I I go for I needed to go for a walk or like hugging a tree or know something that you feel that you are touching nature.

[01:01:44] It feels that you can connect with that inner too. Yeah. 

[01:01:50] Yeah, I so appreciate that because I don't know if you know the term adaptogen. Great. So nature is a very much it, the best adaptogen there is. If you are feeling low, it'll bring you up. If you're feeling arrogant is going to humble you. So it was great.

[01:02:11] Go to nature. Nature is awesome, right? Yeah, exactly. 

[01:02:18] Now some people watching this may be thinking like, man CK is spending a lot of time talking about Carolyn on the individual. The reason I do that is in my mind. What it takes to be a effective leader is fractal. So you have self family, company, country, and the world, right?

[01:02:41] So if we don't have our mindset, correct, if we don't have a higher vibration on an individual basis, you could try to force. And I'll come by having some company, but guess what? We built what we are in any limitations or limiting beliefs or mindset that we have. It's only going to get amplify when the individual isn't solid.

[01:03:08] That's why I spend a lot of time on the individual. I'm curious to know your thoughts currently. Now you're a CEO, right? You're in you and your relationship with three other co-founders what do you think? Do you agree with that? Do you disagree? What do you think. Yeah, definitely. I think you need to be in a stable state and the in that, state of peace to be able to lead a company.

[01:03:43] So that's why. I know that every entrepreneur, they have gone through times that they need to work super hard, long hours. They almost burn out themselves, but it feel if you think that this is a marathon and not a sprint. If you burn out theirself, you're not going to get your company anywhere.

[01:04:06] So taking care of yourself first and making sure that you have not only your mental health your physical health and that you'll know how to inspire and to lead other people to take care of themselves too. So they can be at their best. State to produce into the liver. What your hope from them, for the company?

[01:04:36] I think that's the way that we can really go along the way if we don't if we don't care about no, the foundation. We are not gunna be able to survive the, this marathon. So that's why I, have I need to have my exercising. I am very Rigorous about my diet. I like to bring things to my body that I will feel that also will increase my energy that will boost my health.

[01:05:23] I go to faith I have. I nurture my spirituality because this hours also helps me to keep moving and keep it going through all the hard situations, but also brings me creativity brings me insights. And I usually say that we have a lot of help around those. If we don't use are just not the.

[01:05:53] Making them most that we have available to us. So if, you, if we have this balance of all this pillars that are important to our life, I think you are gonna get to your best self to be the best leader that you can be. Yeah. 

[01:06:15] And on this podcast, we talk a lot about quote unquote, soft skills.

[01:06:20] Th this very thing that we're talking about, the intangibles of spirituality, the emotionality, the communication. Mainly because. The people who watched the show. The, I know you're already smart. I know you can figure things out. I know, you know how to do the quote unquote hard skills, right? And then that's not where you need support either.

[01:06:45] The areas where it's neglected are the quote unquote soft skills, the intangible, the personality. You mentioned the, forgiveness, the self-love, the overcoming imposter syndrome. All of this stuff that we have been talking about, so that's why in my mind, A good combination of the two are important CEO skills.

[01:07:10] Anything else you wanted to talk about in terms of CEO skills before we move on to how you made the co-founder relationship work, anything else on the individual basis, importance to your skills?

[01:07:22]I think Yeah, I think the CEO is that the kind of North star for the company. So you need to be able to said that vision for the company, but also find that everyone that will help you to build the. That value proposition that will make the company to get there and to create the impact that you believe.

[01:08:00] So I think, and this is lots of, so when Now recently when we published this the documentary I was in the meeting before I was appreciating everyone's contribution. And I talk about how everyone, what they were bringing to the team. And one of my co-founders, or let me talk about you, Carol, because I, you also.

[01:08:28] You have this ability of bringing everyone together and aligned to move towards that vision. So I think that's one of the skills of the CEO that's very essential is finding the right people and setting and bringing out them aligned not the only selling the vision and the dream.

[01:08:54] But. Making the impact that we are creating so clear and meaningful to all of them that it's natural for them to work and give their best for, this company or this project. So the fact that we can. Bring people together towards our vision or mission. I think it's something that the CEO needs to be doing everyday.

[01:09:29] I love that. So any exercise books, disciplines rituals, one could take on to practice that skill of enrollment. I call it enrollment. How do you actually inspire them and galvanized their force towards a common vision? Any specific. Practice one can take on to be better at that.

[01:09:54] I think I'm always like learning how or reading how to be a better leader or a better view, the better team. And one thing that I've learned and the. And even for myself as a as an entrepreneur, I need to be able to be vulnerable and be okay with that. And I think in the company is not something that we also created this safe space for people to be themselves so they can be vulnerable.

[01:10:35] So I learned this. Researching best practice for building the best teams the ones that people, they feel that they can be themselves, they don't need to hide, or they are afraid to share something because they will be judged. So I remember this experiment that Google did that, they did this research and they were trying to nail down all the.

[01:11:01] Character is of the best teams and they got to this conclusion and I thought this was, yeah, this makes so much sense. And that's thing, fireman that we'd be able to not company so people can, they feel accepted. They feel it's a very welcoming place for them to be themselves.

[01:11:30] So agree, a hundred percent being compassionate, having psychological having an environment for psychological safety, intellectually agree a hundred percent. So someone who is listening, maybe thinking, especially if they're entrepreneur, tactically, what do they do to cultivate that environment of psychological safety?

[01:11:55]There are several I would say like workshops or group gatherings that you can allow people to talk about. You can ask them. Things that you wouldn't ask in that day today. So if you create those moments that, you that do show that you care about who they are beyond that coworker First time that I think you are gonna get to a level of connection and bonding that they will feel that they belong and they will feel safer.

[01:12:50] So created those kinds of Experiential groups that people can talk about. So you know this unfortunately today it's not the same, but ideally you would go to a retreat or your go to, or something that like people will feel comfortable sharing things that they don't share. No, they today at work.

[01:13:16] Got it. Having the intention of letting you know that, Hey, I care about you. And then ask questions. That's deeper than just quote unquote business specific about the role. It's more about the person, the human being behind the role, and then at some point going to a retreat so they can get to know that person even more on a deeper level.

[01:13:42] And that's what you're saying. Yeah. Yes, that's correct. Oh, that's beautiful. I, so I used to be a chief culture officer in our startup before. And one of the things I realized is this, in addition to having an intention, Hey, I care about you actually say, Hey, I care about you. So there is no question. And it's, also not about just the words.

[01:14:08] It's about the longevity of the word. How much do I say that? And how much do I actually show up for you and how much do I remember to actually. Care about the holistic human being. So in my mind that provides more of a space of psychological safety with me, at least I hope, I it's I'm a very cerebral person so, I have to learn these types of skills as a way to show others that I actually care about you.

[01:14:42] It should give you that psychological safety. Yeah. And I think I've been also learning this, that the best, the way the best leaders they care first, and then they manage a second. So if you show that you care about your employees, your team they will though everything because they will be appreciative for you to care about them.

[01:15:16] That's something that it's, not always obvious. But yeah, I, we can see that the successful leaders say. They showed this very genuine care about their people. 

[01:15:40]So I'm very curious. I used to have a startup company. I'll five co-founders am I? My other co-founder my other entrepreneurial friends is turd about it and they, laughed at me because they thought I was crazy for getting involved with four other people in starting a company.

[01:16:00] And that company exploded. Because of co-founder conflict. And, when I look at you and then you have lasted it's been four years so far, right? Almost five years. Yeah. So in startup land, that's 50 years. So congratulations for lasting 50 years. So what rubric, what operating system, what structured did you have in place to foster a harmonious for people coming together, building something beautiful.

[01:16:40] Yeah. It was not always as a smooth relationship. And this was of one of the learnings that I learned along the way. So when I got together with the first two co-founders to me, they had the same goals. That I had, that was like, I want to dedicate my life to this company. And I would do everything that's possible to make the company succeed.

[01:17:19] And eventually I realized that this was not exactly their goals. And a lot of people, they say that these are not the right co-founders and one could argue that. But it worked. And after talking and after understanding again each of them, they have their own stories and they have their dreams.

[01:17:47] And should they look looking back? I. I clearly see that they are much happier where they are now. So they are not full time. But they are co-founders. They were, we are together in fact for almost seven years now because we had this first company and then we came here. Oh, I see.

[01:18:18] Each other that much, you want to start a second company together. That's great. Yeah. Then the second one was a transition from the first one. But even though we had some there's alignments in the beginning and a lot of them came. Based on the fact that we didn't know what it, requires to build a company or how to do, or what is, what are the best practice.

[01:18:48] So everyone was like trying to say, I think it's this way. I think it's that way. So I think the lack of experience makes things even harder because if I was going to build another company today, I learned so much, so I know. What is, what are the best practice. But what I could find in the end is that I came here by myself.

[01:19:17] And a lot of times I feel, I felt like very lonely when When we were the last company in that and that's why bar I was there by myself, like crying. So I feel, I felt very lonely several times, but I know that if I would like message, you called them, they would be there for me, anytime that I need it.

[01:19:44] So even though they were not like physically present, they did their best to. Helped me from where they were and they bring so such an incredible value in terms of not only expertise, but personality. And I learned so much with them and I really admire them. And eventually I brought another one that we are too.

[01:20:12] They co-founders. So she came after one year that I was here. But we are in the same thought that the same vibration and we even lived together here. So we spent like 24 hours together. And the four of us today, we worked super well together, but it took us a while to understand the. Me and Alessandra, we are accepting the same vibration and Mariani, Juliana.

[01:20:46] They have, there are other dreams and lives, but we could align them with the company's vision. So I think it having a mind open to understand if there is a coma. Place that we can align our goals and dreams and make it to work and be very honest. I think that's the way that you can overcome this challenging situations.

[01:21:20] It requires flexibility. It requires we empathy so much empathy for you to put yourself in their shoes and try to understand why they are making that decision and vice versa. So you can make it work. I don't think one skin would be what it is today, if it's if it wasn't for the four of us, but it definitely was like a roller coaster.

[01:21:58] And there will be always like some founder moments. But today we are much more mature in knowing how to address any situation. And that's why we have a regularly one Oh one before. We will do hold things and not share them. And eventually you explode. So if you have one Oh one, or if you have this openness, you please come to me and say, if you didn't like anything that I said, if I heard too.

[01:22:36] Because if you don't say, I will know it's always better to put things out and try to solve things, not like to accumulate and yeah. And get to a point that You feel that the situation is unbearable? So let me ask you a question. You didn't say this, but this is what I'm hearing in between the lines.

[01:23:03] Do you believe that any personalities can come together through this type of practices or were you just lucky?

[01:23:22] Usually I don't believe in luck. I believe that things happen because I believe in the law of action and reaction. So if these things are happening with me, I think that I made some action that caused his reaction would be. The truth for everyone there. So I think that's a way that people can get the same So, I love that. So the way I articulate, what you just said is you take responsibility for your part to whatever reaction that you have caused and others, and the proactive rituals that you have is. Regular. One-on-ones make sure you say everything that there is to say don't hold it back. So on that note, there sound founders.

[01:24:25] Believe that, Hey, let me say everything. So they bring everything, which is great. Some people, some founders believe, let me just be professional. Let's just talk about the work itself. The underlining things that's ruined below. What's your school of thought everything or professional or less than professional or what's the grade?

[01:24:52] What's the spectrum. Don't say everything. You're I still hold holding thing inside, for yourself and eventually did that. We always stopped affecting your relationship with your co-founder. So you can say whatever you want, how you say and right. The way that his say his work, the can makes a huge difference.

[01:25:18] So learning how to explain. Press, you know your feelings. I feel like that this may not be your intention, but that's how I'm feeling and share this from a very honest way. No one can judge you because you are feeling like it's your feeling. If it's true, it's your feeling you are just sharing and I want to share this because I want to get in that place with you again.

[01:25:47] And I want to be able to talk through this. I love it. Do you mind if we spend a little bit of time about the technical aspect of one skin? Yes. I know normally that's your normal conversation, but I'm still curious about it. So I do want to ask you about those things. So my should share with me and the audience.

[01:26:14]Oh, one thing you said documentary, you said skin is the largest organ in the body. And there's the short term skin health approach versus the long-term skin health approach. Say a little bit more about that because I don't think most people think even in the timescale, the long-term short-term approach to skin health.

[01:26:39] Yeah. As we studied about clean, we not only realize that. Okay. Skin is our largest organ and it's important to keep it, this organ functioning well to protect. So they may, function of this skin is to is our main physical barrier, right? Protects us against infections and all types of stress environmental stress and water loss, and so on.

[01:27:12] Keep our body our temperature. So this is one thing that's super important to our health and a healthy, for example, even like skin cancer is one of the leading cause of cancer. So keeping our skin healthy only for the skin is already important, but not their thing that we realized is studying skin.

[01:27:37] Is that. Since his skin is our largest organ. And as we age our tissues start to secrete inflammation, then levels of inflammation that are coming from the skin and it's influence your body's levels of inflammation. And these inflammation is associated with chronic diseases, such as outside America, cardiovascular disease cancer.

[01:28:09] Can they skein be one of the the drivers of this inflammation, and this can be accelerating the development of chronic diseases or vice versa by keeping our skin healthier. Can we prevent or delay those detrimental diseases. So right now, if that's this case and it makes a lot of sense that's the case, everyone should take care of their skin and mainly.

[01:28:45] After your fifties, after thirties you, really start, you see a shift to in terms of the dysfunction, but after your fifties, you really see this levels like bracing of inflammation rising. And that's when it should be like mandatory men women care about beauty appearance.

[01:29:06] Doesn't matter. I'm sure that you care about not developing cardiovascular outsider or cancer. So that's the most interesting connection that we, where you were founding. And there is even this experiment at the UCSFs where they treated like. I think it was like 30 patients for one month. So they applied this cream topically twice a day and this cream was supposed to improve the skin barrier.

[01:29:37] And after one month they measured the levels of inflammation in their blood and they saw that this levels decreased. To a level of a person around 30 years and they were on there for 50 years. So that means that treating your skin, you can decrease the levels of inflammation in your blood. So that's very interesting because that's what we want to to demonstrate, to validate how we are all connected.

[01:30:10] Our tissues are connected and If w if we can do everything right if you, take supplements to keep her body health healthy and functioning better, why you don't have a supplement for your skin? That's your largest organ. That's what one skin is working on right now. That's actually really interesting cause I consider myself a biohacker right.

[01:30:37] So I actually think about how do I optimize my internal health and to be really Frank here and publicly, I don't apply sunblock at all. And I don't even think about the, whole idea of internal inflammation. So it wasn't interior with the way you said it. They're like, Oh yeah, that makes a lot of sense.

[01:30:57] How can I take care of my my diet? Sugar things like that. So then I don't actually inherently fostering the internal environment to have more inflammation internally. That's very insightful. Thank you. Yes. And I to be honest, Al I had not made this connection until I started studying this field so I totally understand that 90 to 9% don't make this connection.

[01:31:27] And that's one of our job here is like to be able to share and to bring this knowledge is so people can start to take action. So you have an interesting approach. There's a word I never said that I never recognized before until I started researching our conversation. Citizen cells. Can you say a little bit more about what that is?

[01:31:53] Yes. So senescent cells are cells that have replicated a lot. So in our body, usually a cell is Replicating. And then eventually the sales rates, the limit and this cell should die, or the cells should sometimes they become a cancer or they enter in this state called the cellular senescence. That's basically a cell arrest.

[01:32:20] So the cell can't replicate anymore. But they start to create inflammatory signals. So they work like a bad Apple in a basket. So one senescent cells releases inflammation and contaminate cells around. And this leads to tissue dysfunction and this accumulation of centers and cells is associated with numerous age-related diseases.

[01:32:47] So what they found is that. Those cells accumulate in our giants, in our heart, in our brain. And they are associated with most of the diseases that we are trying to treat. And one way that we could work or solve this problem is to eliminate senescent cells. So there are drugs that can specifically induce the death of senators and cells or.

[01:33:15] Help your body like boost your body's efficient. So you don't form senescence cells because senescent cells are cells that have accumulated a lot of damage. And this damage also accumulates because your repair system is effective. So for example, our technology helps yourself to be more effective, so it can repair those damage.

[01:33:42] And then the cell doesn't go to the center since it's state. And by preventing the formation of senescent cells, we can extend the time that our tissues are healthy and functional.

[01:34:00] The layman term for that is zombie cells, right? Zombies sounds. Yeah. They look like consomme. This cells, they half life, half that cells, but they are sick, creating bad fives and we don't. Yeah, we don't want,  building up in our bodies. And then you guys have discover a unique pack tie, always one as a way to eliminate partially or regulate these a senescent cell.

[01:34:33] Can you say a little bit more about that? Sure. So when we decided to focus or to address skin aging We decided to understand what was the underlying cause of skin age. And then we saw that there was a common causes of aging that sent us and sales was one of those causes. And so we did so since we want to address skin aging to the molecular level, we decided to.

[01:35:07] Field, they screening platform where we tested more than a thousands of compounds of thousands of peptides. And then we found  Swan. That was the one that was more effective in decreasing the level of senescence cells in the skin. And that's the molecule that we have later validated in different types of aging scan.

[01:35:35] And then we have formulated this peptide in a topical cream. We tested in humans. We could not only see any improvement in the skin barrier. So it was really treating the skin and improving the function of the skin. But also was ameliorating the the external aspect of the skin. So your skin was looking like better, it's more there younger.

[01:36:01] So that's how quick question about the timeline effect? Cause you had said in your presentation, your documentary is that other companies are treating it with, let's say Botox, laser, things like that. And then are actually. Not necessarily conducive to the long-term benefits. But they're able to show their clients any immediate improvement.

[01:36:27] So tell us a little bit about the difference between how long does it take for one skin cream to show the benefit because as the inside out approach longterm effect versus others, just out of curiosity, I'm curious to know what's, your take on right? Yeah. So in vitro. So in the lab, when we test or Swan in the skins that we grow, or even in pieces of a human skin that we get from leftover of plastic surgeries, we can see that we can.

[01:37:05] Promote effects like as fast as five days. So we can measure the the thickness of the skin. We can measure the biological age of the scan and we can see that we are really decreasing the biological invisible. We have seen that. It takes like from one to three months for people to start seeing the results.

[01:37:28] But since we are constantly being exposed to stress, and then the more that you use, the more your cell will be better prepared the, to repair the damage. So you. You'll keep like strengthening your tissue as you use this product over time, it's a, the default is to age, but if you have a field that you can give to yourself, so your cell keeps like working properly.

[01:38:08] You'll see over time, if you use the product or don't use. A very significant difference because you are keeping this system that is working or you were boosting your set yourself and your and your repair mechanisms to be working properly. The longer, the better I've been using the product for.

[01:38:38] Maybe 18 months right now. I'm 53, by the way.

[01:38:50] Just kidding. But yeah, we have great results. So it varies from person to person. Some people see like very fast in two weeks, some people take more time. But the, what we can really make sure that if If we test in the lab and if we show in field days, we can show and we can really show the difference.

[01:39:14] We can show the control and we can show the treated, and we can show the data to those that want to understand the better So, let me ask you a question because you had alluded to earlier, Hey, I applied this topically and in my internal inflammation has gone down systematically, right?

[01:39:32] So is it, Hey, I just applied to my face and then this area will have better skin, but the rest is okay. Or. My entire skin needs to be applied in this thing. And then the more the merrier let me apply it three times a day or whatever, curious to know the effect of applying locally versus this systematically.

[01:39:58]It does make sense that you apply throughout your whole body. We are starting with a cream for the face, hands and neck, because are there areas that are most exciting? Both to the damage.

[01:40:13] But our next product should be a product in order to applying the whole body. So as for younger people, I, we usually age festers in the areas that are exposed. So yeah. And the parts and things also to keep your skin hydrated. And year old body with ever a moisturizer that you use, but in the future, we want to be able to bring this, that tide in the product that will also help in repairing them and really being systemic.

[01:40:53]Carlina, there's so many other questions I want to do follow up with you around the business model around cause you mind my right away. I saw the internet comments about the possibility of this product.

[01:41:06] A lot of women are really excited about finally a molecular based or STEM cell based anti-aging cream and right away they ask, where can I go get it right? Where can I order this? So right away as a, business person, I think. This company proactive, I don't know if you know them. They started by Stanford, PhD researchers and then turned into, I don't know, gazillion billion dollar business.

[01:41:33] And this is what I think about Oh yeah. So the technology's here. How, can the audience help? Yeah, go online. And what are those and anything that, could support the mission that you have in turning this into an anti-aging company, even more successful than it is today.

[01:41:56] Yeah, it's help us to spread the word. I think a one scan is much more than a product, so we bring a lot of information in terms of notice and knowledge that we have today that can help us make better choices to live a healthier longer. So equally think that our. But purpose is valid and you're not only I trust their product, but also in nurturing yourself with information, help us to share this and bring this your family and, bring this conversation around aging.

[01:42:41] Like. How are we dealing with aging today? Are we being passive or are being pro active and doing something about it that so many ways that we can age and it will depend on the choices that we are doing. They, so if we are powered by information and you feel bring your family and your friends and your.

[01:43:11] Spouse comfort. They then can take action to get I think these will be able to chill. We will be able to impact more and more people and we'll be able to defend restructure our healthcare system. We don't want to be spending hundreds of billions. Two in the last six months of our lives, we want to spend hundreds of billions to build technology and education and build like a better. Way of living to everyone for the most part of our lives. So I think this conversation needs to be needs to include that for one. And I would really appreciate if you guys help sharing their words.

[01:44:05] Amazing. Hey curly. I want to take a moment to really acknowledge you for just sharing your life story. The warrior spirit was strong in you. You came to this country by yourself. You, share so generously about. In some of the dark moments that you had and the inspiration that you have, the practices that you have to keep yourself at a higher vibrational level and bring all of your co-founders together and continue galvanizing this momentum behind you, to where it is today.

[01:44:37] I'm really, excited about the possibility of one skin. Personally, I'm like, yeah, I want to look great. And I want to be able to even reverse aging, so I can. Reverse the damage that I've done to my own skin and the rest of my body as well. So just really, appreciate you showing up and being able to dance with me.

[01:45:00] Yeah, it is a great conversation. Thank you so much. It's for those moments, I think it may. It makes everything like more meaningful looking back and sometimes we start like complaining, right? Oh, this is going wrong, but I've been to a much worse situation. So looking back and realizing how much we have overcome over the time over the years great way also to.

[01:45:34] Be grateful for what we have today. So thanks for this opportunity. And yeah, congrats on this beautiful work that you're doing. Thank you.

 

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